This unfortunate wealthy wanderer made a virtual mark in United states by huge donations and studied Tabasheer from India

James Smithson(1765 – 27 June 1829) was an English chemist and mineralogist. He was the founding donor of the Smithsonian Institution.

Smithson was the illegitimate child of the 1st Duke of Northumberland, and was born secretly in Paris, as James Lewis Macie. Eventually he was naturalized in England and he attended college, studying chemistry and mineralogy. At the age of twenty-two, he changed his surname from Macie to Smithson, his father's surname. Smithson traveled extensively throughout Europe publishing papers about his findings. Smithson became the founding donor of the Smithsonian Institution in Washington, D.C.; however he never visited the United States.

Smithson was nomadic in his lifestyle, traveling throughout Europe. As a student, in 1784, he participated in a geological expedition with Barthélemy Faujas de Saint-Fond, William Thornton and Paolo Andreani of Scotland and the Hebrides. He was in Paris during the French Revolution.

Smithson's research work was eclectic. He studied subjects ranging from coffee making to the use of calamine in making brass, which would eventually be called smithsonite. He also studied the chemistry of human tears, snake venom and other natural occurrences. Smithson would publish twenty-seven papers. He was nominated to the Royal Society of London. Smithson socialized and worked with scientists Joseph Priestley, Sir Joseph Banks, Antoine Lavoisier, and Richard Kirwan.

His first paper was presented at the Royal Society on July 7, 1791, "An Account of Some Chemical Experiments on Tabasheer." Tabasheer is a substance used in traditional Indian medicine and derived from material collected insides bamboo culms. The samples that Macie analyzed had been sent by Patrick Russell, physician-naturalist in India. 

In 1802 he read his second paper, "A Chemical Analysis of Some Calamines," at the Royal Society. In the paper, Smithson challenges the idea that the mineral calamine is an oxide of zinc. His discoveries made calamine a "true mineral." He explored and examined Kirkdale Cave and published about his findings in 1824. His findings successfully challenged previous beliefs that the fossils within the formations at the cave were from the Great Flood. Smithson is credited with first using the word "silicates".

Smithson died in Genoa, Italy on June 27, 1829. He was buried in Sampierdarena in a Protestant cemetery. It was not until 1835 that the United States government was informed about the bequest. A committee was organized and the Smithsonian Institution was founded. Smithson's estate was sent to the United States, accompanied by Richard Rush. The estate arrived as gold sovereigns in eleven boxes. Smithson's personal items, scientific notes, minerals, and library also traveled with Rush. This final amount totaled $54,165.38.

Tabasheer or Banslochan, also spelt as Tabachir or Tabashir, is a translucent white substance, composed mainly of silica and water with traces of lime and potash, obtained from the nodal joints of some species of bamboo. It is part of the pharmacology of the traditional Ayurvedic and Unani systems of medicine of the Indian subcontinent. It is also an ingredient in many traditional Chinese medicines.

Tabasheer is referred to as Tvaksheera in Sanskrit, which means bark milk. Other Sanskrit-derived names have been applied to tabasheer as well, including bamboo sugar (vans-sharkar), bamboo camphor (vans karpoor) and bamboo manna. It is called Tian Zhu Huang in Mandarin, which means "heavenly bamboo yellow."

Tabasheer is claimed to provide a variety of health benefits. It is variously regarded as an antipyretic, antispasmodic,antiparalytic, restorative and aphrodisiac. Tabasheer that has a blueish tint (usually called neel or neelkanth) is considered superior to tabasheer that has the "more plain" yellow or white color. Not all bamboo stems contain tabasheer. Likely candidates are found by shaking bamboo stems, which can make the mineralized tabasheer inside produce a rattling sound. These stems are split open to extract the tabasheer.

Although a part of the ancient Ayurvedic system of medicine, it has been postulated that the use of tabasheer originated in the Adivasi aboriginal tribes of India. Tabasheer was extensively exported from India for thousands of years, including through Arab traders during the medieval period. The town of Thane, close to the west coast of India, was famous as a clearing center for tabasheer in the twelfth century CE. It was called σάκχαρον in the writings of Pedanius Dioscorides, aGreek pharmacologist who practiced in Rome in the time of Nero.

This fellow discovered COBALT in ancient times!!!

Georg Brandt (26 June 1694 – 29 April 1768) was a Swedish chemist and mineralogist who discovered cobalt (c.1735). He was the first person to discover a metal unknown in ancient times.

Brandt was born in Riddarhyttan, Skinnskatteberg parish, Västmanland to Jurgen Brandt, a mineowner and pharmacist, and Katarina Ysing. He was professor of chemistry at Uppsala University, and died in Stockholm. He was able to show that cobalt was the source of the blue color in glass, which previously had been attributed to the bismuth found with cobalt. He died on April 29, 1768 of prostate cancer.

About 1741 he wrote: "As there are six kinds of metals, so I have also shown with reliable experiments... that there are also six kinds of half-metals: a new half-metal, namely Cobalt regulus in addition to Mercury, Bismuth, Zinc, and the reguluses of Antimony andArsenic". He gave six ways to distinguish bismuth and cobalt which were typically found in the same ores:

1. Bismuth fractures while Cobalt is more like a true metal.
2. In fusing, they do not mingle but attach about as an almond and its stone.
3. The regulus of Cobalt fuses with flint and fixed alkali giving a blue glass known as zaffera, sasre, or smalt. Bismuth does not.
4. Bismuth melts easily and if kept melted, calcinates forming a yellow powder.
5. Bismuth amalgamates with Mercury; the regulus of Cobalt does not at all.
6. Bismuth dissolved in nitric acid and with aqua regia and gives a white precipitate when put in pure water. The regulus of Cobalt needs alkalies to precipitate, and then forms dark or black precipitates.

Finding out about electricity in human body in that era was astounding!!!

Carlo Matteucci (June 21, 1811 - June 25, 1868) was an Italian physicist and neurophysiologist who was a pioneer in the study of bioelectricity. Carlo Matteucci was born at Forlì, in the province of Romagna, to Vincenzo Matteucci, a physician, and Chiara Folfi. He studied mathematics at the University of Bologna from 1825 to 1828, receiving his doctorate in 1829. From 1829 to 1831 he studied at the École Polytechnique in Paris, France. 

Upon returning to Italy, Matteucci studied at Bologna (1832), Florence, Ravenna (1837) and Pisa. He established himself as the head of the laboratory of the Hospital of Ravenna and became a professor of physics at the local college. In 1840, by recommendation of François Arago (1786–1853), his teacher at the École Polytechnique, to the Grand-Duke ofTuscany, Matteucci accepted a post of professor of physics at the University of Pisa.

Instigated by the work of Luigi Galvani (1737–1798) on bioelectricity, Matteucci began in 1830 a series of experiments which he pursued until his death in 1865. Using a sensitive galvanometer of Leopoldo Nobili, he was able to prove that injured excitable biological tissues generated direct electrical currents, and that they could be summed up by adding elements in series, like in Alessandro Volta’s (1745-1827) electric pile. 

Thus, Mateucci was able to develop what he called a "rheoscopic frog", by using the cutnerve of a frog’s leg and its attached muscle as a kind of sensitive electricity detector. His work in bioelectricity influenced directly the research developed by Emil du Bois-Reymond (1818–1896), a student of the great German biologist Johannes Peter Müller (1801–1858) in Berlin, who tried the duplicate Matteucci’s experiments and ended up discovering the nerve's action potential. 

In 1844, for these studies, Matteucci was awarded with the Copley medal by the Royal Society. From 1847 he took an active part in politics, and in 1860 was chosen an Italian senator, at the same time becoming inspector-general of the Italian telegraph lines. Two years later he was appointed Minister of Education. Matteucci died in Ardenza, near Livorno, in 1868.

This AUSTRIAN wandered & discovered the cosmic rays!!!

Victor Francis Hess (24 June 1883 – 17 December 1964) was an Austrian-American physicist, and Nobel laureate in physics, who discovered cosmic rays. Born to Vinzenz Hess and Serafine Edle von Grossbauer-Waldstätt, in Waldstein Castle, near Peggau in Styria, Austria on 24 June 1883. He attended secondary school at Graz Gymnasium from 1893 to 1901.

From 1901 to 1905 Hess was an undergraduate student at the University of Graz, and continued postgraduate studies in physics until he received his PhD there in 1910. He worked as Assistant under Stefan Meyer at the Institute for Radium Research, Viennese Academy of Sciences, from 1910 to 1920. In 1920 he married Marie Bertha Warner Breisky.

Hess took a leave of absence in 1921 and traveled to the United States, working at the US Radium Corporation, in New Jersey, and as Consulting Physicist for the US Bureau of Mines, in Washington DC. In 1923, he returned to the University of Graz, and was appointed the Ordinary Professor of Experimental Physics in 1925. The University of Innsbruck appointed him Professor, and Director Institute of Radiology, in 1931.

Hess relocated to the United States with his Jewish wife in 1938, in order to escape Nazi persecution. The same year Fordham University appointed him Professor of Physics, and he later became a naturalized United States citizen in 1944.  In 1946 he wrote on the topic of the relationship between science and religion in his article "My Faith", in which he explained why he believed in God. He retired from Fordham University in 1958 and he died on 17 December 1964, in Mount Vernon, New York from Parkinson's disease.

Between 1911 and 1913, Hess undertook the work that won him the Nobel Prize in Physics in 1936. For many years, scientists had been puzzled by the levels of ionizing radiation measured in the atmosphere. The assumption at the time was that the radiation would decrease as the distance from the earth, the source of the radiation, increased. 

The electroscopes previously used gave an approximate measurement of the radiation, but indicated that higher in the atmosphere the level of radiation may actually be more than that on the ground. Hess approached this mystery first by greatly increasing the precision of the measuring equipment, and then by personally taking the equipment aloft in a balloon. He systematically measured the radiation at altitudes up to 5.3 km during 1911-12. The daring flights were made both at day and during the night, at significant risk to himself.

The result of Hess's meticulous work was published in the Proceedings of the Viennese Academy of Sciences, and showed the level of radiation decreased up to an altitude of about 1 km, but above that the level increased considerably, with the radiation detected at 5 km about twice that at sea level. 

His conclusion was that there was radiation penetrating the atmosphere from outer space, and his discovery was confirmed by Robert Andrews Millikan in 1925, who gave the radiation the name "cosmic rays". Hess's discovery opened the door to many new discoveries in particle and nuclear physics. In particular, both the positron and the muon were first discovered in cosmic rays by Carl David Anderson. Hess and Anderson shared the 1936 Nobel Prize in Physics.

This AUSTRIAN wandered & discovered the cosmic rays!!!

Victor Francis Hess (24 June 1883 – 17 December 1964) was an Austrian-American physicist, and Nobel laureate in physics, who discovered cosmic rays. Born to Vinzenz Hess and Serafine Edle von Grossbauer-Waldstätt, in Waldstein Castle, near Peggau in Styria, Austria on 24 June 1883. He attended secondary school at Graz Gymnasium from 1893 to 1901.

From 1901 to 1905 Hess was an undergraduate student at the University of Graz, and continued postgraduate studies in physics until he received his PhD there in 1910. He worked as Assistant under Stefan Meyer at the Institute for Radium Research, Viennese Academy of Sciences, from 1910 to 1920. In 1920 he married Marie Bertha Warner Breisky.

Hess took a leave of absence in 1921 and traveled to the United States, working at the US Radium Corporation, in New Jersey, and as Consulting Physicist for the US Bureau of Mines, in Washington DC. In 1923, he returned to the University of Graz, and was appointed the Ordinary Professor of Experimental Physics in 1925. The University of Innsbruck appointed him Professor, and Director Institute of Radiology, in 1931.

Hess relocated to the United States with his Jewish wife in 1938, in order to escape Nazi persecution. The same year Fordham University appointed him Professor of Physics, and he later became a naturalized United States citizen in 1944.  In 1946 he wrote on the topic of the relationship between science and religion in his article "My Faith", in which he explained why he believed in God. He retired from Fordham University in 1958 and he died on 17 December 1964, in Mount Vernon, New York from Parkinson's disease.

Between 1911 and 1913, Hess undertook the work that won him the Nobel Prize in Physics in 1936. For many years, scientists had been puzzled by the levels of ionizing radiation measured in the atmosphere. The assumption at the time was that the radiation would decrease as the distance from the earth, the source of the radiation, increased. 

The electroscopes previously used gave an approximate measurement of the radiation, but indicated that higher in the atmosphere the level of radiation may actually be more than that on the ground. Hess approached this mystery first by greatly increasing the precision of the measuring equipment, and then by personally taking the equipment aloft in a balloon. He systematically measured the radiation at altitudes up to 5.3 km during 1911-12. The daring flights were made both at day and during the night, at significant risk to himself.

The result of Hess's meticulous work was published in the Proceedings of the Viennese Academy of Sciences, and showed the level of radiation decreased up to an altitude of about 1 km, but above that the level increased considerably, with the radiation detected at 5 km about twice that at sea level. 

His conclusion was that there was radiation penetrating the atmosphere from outer space, and his discovery was confirmed by Robert Andrews Millikan in 1925, who gave the radiation the name "cosmic rays". Hess's discovery opened the door to many new discoveries in particle and nuclear physics. In particular, both the positron and the muon were first discovered in cosmic rays by Carl David Anderson. Hess and Anderson shared the 1936 Nobel Prize in Physics.

This gifted virologist gave away normal practice to work for a bigger cause and developed POLIO vaccines despite difficulties!!!

Jonas Edward Salk (October 28, 1914 – June 23, 1995) was an American medical researcher and virologist. He discovered and developed the first successful inactivated polio vaccine. He was born in New York City to Jewish parents. Although they had little formal education, his parents were determined to see their children succeed. While attending New York University School of Medicine, Salk stood out from his peers, not just because of his academic prowess, but because he went into medical research instead of becoming a practicing physician.

As a child, Salk did not show any interest in medicine or science in general. He said in an interview with the Academy of Achievement "As a child I was not interested in science. I was merely interested in things human, the human side of nature, if you like, and I continue to be interested in that."

At his mother's urging, he put aside aspirations of becoming a lawyer, and instead concentrated on classes necessary for admission to medical school. However, according to Oshinsky, the facilities at City College of New York were "barely second rate." There were no research laboratories. The library was inadequate. The faculty contained few noted scholars. 

"What made the place special," he writes, "was the student body that had fought so hard to get there ... driven by their parents... From these ranks, of the 1930s and 1940s, emerged a wealth of intellectual talent, including more Nobel Prize winners—eight—and PhD recipients than any other public college except the University of California at Berkeley." Salk entered City College at the age of 15, a "common age for a freshman who had skipped multiple grades along the way."

During Salk's years at the New York University School of Medicine, he stood out from his peers, according to Bookchin, "not just because of his continued academic prowess—he was Alpha Omega Alpha, the Phi Beta Kappa Society of medical education—but because he had decided he did not want to practice medicine." Instead, he became absorbed in research, even taking a year off to study biochemistry. 

He later focused more of his studies on bacteriology which had replaced medicine as his primary interest. He said his desire was to help humankind in general rather than single patients. And as Oshinsky writes, "it was the laboratory work, in particular, that gave new direction to his life."

Until 1957, when the Salk vaccine was introduced, polio was considered the most frightening public health problem of the post-war United States. Annual epidemics were increasingly devastating. The 1952 epidemic was the worst outbreak in the nation's history. Of nearly 58,000 cases reported that year, 3,145 people died and 21,269 were left with mild to disabling paralysis, with most of its victims being children. The "public reaction was to a plague," said historian Bill O'Neal. 

"Citizens of urban areas were to be terrified every summer when this frightful visitor returned." According to a 2009 PBS documentary, "Apart from the atomic bomb, America's greatest fear was polio." As a result, scientists were in a frantic race to find a way to prevent or cure the disease. U.S. president Franklin D. Roosevelt was the world's most recognized victim of the disease and founded the organization, the March of Dimes Foundation, that would fund the development of a vaccine.

In 1947, Salk accepted an appointment to the University of Pittsburgh School of Medicine. In 1948, he undertook a project funded by the National Foundation for Infantile Paralysis to determine the number of different types of polio virus. Salk saw an opportunity to extend this project towards developing a vaccine against polio, and, together with the skilled research team he assembled, devoted himself to this work for the next seven years. 

The field trial set up to test the Salk vaccine was, according to O'Neill, "the most elaborate program of its kind in history, involving 20,000 physicians and public health officers, 64,000 school personnel, and 220,000 volunteers." Over 1,800,000 school children took part in the trial. 

When news of the vaccine's success was made public on April 12, 1955, Salk was hailed as a "miracle worker," and the day "almost became a national holiday." His sole focus had been to develop a safe and effective vaccine as rapidly as possible, with no interest in personal profit. When he was asked in a televised interview who owned the patent to the vaccine, Salk replied: "There is no patent. Could you patent the sun?"

In 1960, he founded the Salk Institute for Biological Studies in La Jolla, California, which is today a center for medical and scientific research. Salk's last years were spent searching for a vaccine against HIV. His personal papers are stored at the University of California, San Diego Library.

He stepped ahead from FASTENING to ZIPPING !!!

Gideon Sundback (April 24, 1880 – June 21, 1954) was a Swedish-American electrical engineer, who is most commonly associated with his work in the development of the zipper. Otto Fredrik Gideon Sundback was born on Sonarp farm in Ödestugu Parish, in Jönköping County, Småland, Sweden. He was the son of Jonas Otto Magnusson Sundbäck, a prosperous farmer, and his wife Kristina Karolina Klasdotter. After his studies in Sweden, Sundback moved to Germany, where he studied at the polytechnic school in Bingen am Rhein. In 1903, Sundback took his engineer exam. In 1905, he emigrated to the United States.

In 1905, Gideon Sundback started to work at Westinghouse Electric and Manufacturing Company in Pittsburgh, Pennsylvania. In 1906, Sundback was hired to work for the Universal Fastener Company of Hoboken, New Jersey. Subsequently in 1909, Sundback was promoted to the position of head designer at Universal Fastener.

Sundback made several advances in the development of the zipper between 1906 and 1914, while working for companies that later evolved into Talon, Inc. He built upon the previous work of other engineers such as Elias Howe, Max Wolff, and Whitcomb L. Judson.

He was responsible for improving the "Judson C-curity Fastener". At that time the company's product was still based on hooks and eyes. Sundback developed an improved version of the C-curity, called the "Plako", but it too had a strong tendency to pull apart, and was not any more successful than the previous versions. Sundback finally solved the pulling-apart problem in 1913, with his invention of the first version not based on the hook-and-eye principle, the "Hookless Fastener No. 1". He increased the number of fastening elements from four per inch to ten or eleven. 

His invention had two facing rows of teeth that pulled into a single piece by the slider, and increased the opening for the teeth guided by the slider. In 1914, Sundback developed a version based on interlocking teeth, the "Hookless No. 2", which was the modern metal zipper in all its essentials. In this fastener each tooth is punched to have a dimple on its bottom and a nib or conical projection on its top. The nib atop one tooth engages in the matching dimple in the bottom of the tooth that follows it on the other side as the two strips of teeth are brought together through the two Y channels of the slider. The teeth are crimped tightly to a strong fabric cord that is the selvage edge of the cloth tape that attaches the zipper to the garment, with the teeth on one side offset by half a tooth's height from those on the other side's tape. They are held so tightly to the cord and tape that once meshed there is not enough play to let them pull apart. A tooth cannot rise up off the nib below it enough to break free, and its nib on top cannot drop out of the dimple in the tooth above it. U.S. Patent 1,219,881 for the "Separable Fastener" was issued in 1917.

The name zipper was created in 1923 by B.F. Goodrich, who used the device on their new boots. Initially, boots and tobacco pouches were the primary use for zippers; it took another twenty years before they caught on in the fashion industry. About the time of World War II the zipper achieved wide acceptance for the flies of trousers and the plackets of skirts and dresses.

Sundback also created the manufacturing machine for the new zipper. Lightning Fastener Company, one early manufacturer of the zipper, was based in St. Catharines, Ontario. Although Sundback frequently visited the Canadian factory as president of the company, he resided in Meadville, Pennsylvania and remained an American citizen. Sundback was awarded the Gold Medal of the Royal Swedish Academy of Engineering Sciences in 1951. Sundback died of a heart condition in 1954 and was interred at Greendale Cemetery in Meadville, Pennsylvania.

The patent for the "Separable Fastener" was issued in 1917. Gideon Sundback also created the manufacturing machine for the new device. The "S-L" or "scrapless" machine took a special Y-shaped wire and cut scoops from it, then punched the scoop dimple and nib, and clamped each scoop on a cloth tape to produce a continuous zipper chain. Within the first year of operation, Sundback's machinery was producing a few hundred feet (around 100 meters) of fastener per day.

A zipper, zip, fly or zip fastener, formerly known as a clasp locker, is a commonly used device for binding the edges of an opening of fabric or other flexible material, as on a garment or a bag. It is used in clothing (e.g., jackets and jeans), luggage and other bags, sporting goods, camping gear (e.g. tents and sleeping bags), and other items. Whitcomb L. Judson was an American inventor from Chicago who was the first to invent, conceive of the idea, and to construct a workable zipper. The method, still in use today, is based on interlocking teeth. Initially it was called the “hookless fastener” and was later redesigned to become more reliable.